Grapefruit juice interacts with certain enzymes in the intestines, which can cause the body to absorb too much of a medication. View abstract. Effects of citrus fruit juices on cytotoxicity and drug transport pathways of Caco-2 cell monolayers. Rodrigues, A., Brun, H., and Sandstrom, A. Acta Odontol.Latinoam. Some people are sensitive to lime oil when it is applied directly to the skin. home However, grapefruit juice does have an effect on more than 50 drugs, including some medications for the treatment of: Oranges, lemons, and limes are less likely to interact with medications. Before taking lime, talk to your healthcare provider if you are taking any medications that are changed by the liver. View abstract. (1) In the past few years however, new research has shown In addition, drinking it may stop your medication from working altogether, according to scientists—and it's not just opioids. J.Ethnopharmacol. Bailey DG, Dresser GK, Bend JR. Bergamottin, lime juice, and red wine as inhibitors of cytochrome P450 3A4 activity: comparison with grapefruit juice. Keep in mind that natural products are not always necessarily safe and dosages can be important. 4950 views Answered Dec 8, 2020. 1998;28(4):247-248. Drinking lime juice while taking some medications that are broken down by the liver can increase the effects and side effects of these medications. eMedicineHealth does not provide medical advice, diagnosis or treatment. does squirt soda contain enough grapefruit juice to interact with medications like viagra (sildenafil)? The FDA warns that consuming grapefruit at a different time than taking medication does not prohibit adverse reactions. Bailey DG, Dresser GK, Bend JR. Bergamottin, lime juice, and red wine as inhibitors of cytochrome P450 3A4 activity: comparison with grapefruit juice. Two major grapefruit juice components differ in time to onset of intestinal CYP3A4 inhibition. Before taking lime, talk to your healthcare provider if you are taking any medications that are changed by the liver. Your physician might give you a prescription for amlodipine for other health conditions such as angina 1.Amlodipine is a calcium channel blocker that reduces blood pressure by dilating your blood vessels 1.Discuss the use of herbs and amlodipine with … Lime oil might also increase your sensitivity to sunlight. Examples of common medications that interact with grapefruit juice include certain statin cholesterol drugs such as atorvastatin (Lipitor), lovastatin, simvastatin (Zocor), felodipine (Plendil) and other calcium channel blockers, clarithromycin (Biaxin), and loratadine (Claritin). Not in the: Amounts normal humans can consume. Gharagozloo, M. and Ghaderi, A. Immunomodulatory effect of concentrated lime juice extract on activated human mononuclear cells. (5) Predictions in the Canadian Medial Association Journal estimate that more than 85 drugs are known or are predicted to interfere with grapefruit due to this substrate. Pharm.Res. This would also be beneficial to assist your body's … Before taking lime, talk to your healthcare provider if you are taking any medications that are changed by the liver. Should I also stay away from pomelo? View abstract. Aug. 19, 2008 -- Grapefruit, orange, and apple juices block drugs commonly used to treat infections, allergy, transplant rejection, cancer, and high blood pressure. But when on certain medications, … View abstract. 2003;78(2):267-273. B., and Watkins, P. B. Copyright © 2021 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. A 43-year-old male asked: is beet juice really good for lowering blood pressure? 2001;77(1):85-90. Be sure to wear sunblock and protective clothing when spending time in the sun. Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locater Tool Including 24 Hour, Pharmacies. Applying lime oil directly to the skin is POSSIBLY UNSAFE. Always inform your doctor of all herbal supplements you are taking. Drinking lime juice while taking some medications that are broken down by the liver can increase the effects and side effects of these medications. If there i… A. View abstract. Keep in mind that natural products are not always necessarily safe and dosages can be important. 58 years experience Pediatrics. What are other fruits that can interact with medications? 2001;77(1):85-90. 1 doctor answer • 1 doctor weighed in. Some fruit juices and fruits can interact with numerous drugs, in many cases causing adverse effects. 1 ):42-50, drinking it may increase the effects and side of... And even marmalade handles the Lipitor I take for my cholesterol too … Ask the doctor: does juice. 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